GC-FTIR Potential for Structure Elucidation

Elucidation of a polychlorinated bipyrrole structure using enantioselective GC.

A hexachloro congener (Q1-hex) of the natural heptachloro-1'-methyl-1,2'-bipyrrole Q1 was recently observed as a byproduct of the Q1 synthesis. NMR investigation confirmed that Q1-hex has a proton on a carbon in beta-position to a nitrogen. Three isomers are possible that fulfill this prerequisite; unfortunately, however, the NMR data were not sufficient to distinguish among the three structura...

Polymer Analysis Using Pyrolysis-GC-FTIR-MS and GC-AED

GC/MS and GC/FTIR as Powerful Tools for Identifying Bioactive Compounds

Amphetamine-type stimulants (ATS) are a group of substances, mostly synthetic in origin, that generally stimulate the central nervous system. Chemical modification of their molecular structure results in a practically unlimited number of pharmacologically active compounds, some of which are more potent stimulants than others. The gas chromatography combined with mass spectrometry (GC/MS) and, m...

High-resolution FTIR imaging of colon tissues for elucidation of individual cellular and histopathological features.

Novel technologies that could complement current histopathology based cancer diagnostic methods are under examination. In this endeavour mid-infrared spectroscopic imaging is a promising candidate that can provide valuable bio-molecular information from unstained cells and tissues in a rapid and a non-destructive manner. With this imaging technique, the biochemical information obtained from sma...

Structure Elucidation of a New

In the course of our continuing search for novel antimicrobial agents,1-4) we have isolated a novel diketopiperazine, Sch 725418 (1), from culture Micromonospora sp. In this paper, we describe the isolation and structure elucidation of 1 using high resolution ESI-MS and extensive NMR spectroscopic analysis. Fermentation studies of the SP culture 94-00889 were carried out in shake flasks. Stock ...